Muay Thai will definitely make your muscles sore for a while especially if you're new to the sport. The short answer is yes you can KO someone with one punch in MMA, and the strikes you learn in Muay Thai training and Western boxing are the best for the job, however, for this to be accomplished there are several factors that must be present:. In martial arts and similar sports like Muay Thai and Karate various types of gears including standing and heavy apparatus are being used for practicing kicks and improving striking ability.